I try different things.  My favorite setup is to use a guitar with a bridge pickup, and direct input that.  Along with that, I use two SM57's.  On is at 45 degrees pointed up the neck positioned about 8 inches from the bridge.  The other is pointed down the neck at 45 degrees about a quarter down the neck from the nut.

If I can get a third mike, I'll record it for ambiance.  This is only useful in a room with good acoustics.  I'll keep it about 4 feet away in front of me, high and pointed down towards the body of the guitar.

So you'll end up with three or four tracks.  I'd leave the miked tracks dry or add some eq to them.  The DI (given that you have a good bridge pickup) should be where you should work from.

I think this is a topic which changes from person to person.  I find that certain setups don't sound good to me, while other people like them.  It really depends on the sound you are going for and the style of music that you like.

Good luck.